Nur77 serves as a molecular brake of the metabolic switch

nuri77Nur77-GFP reporter mice as a useful tool study Nur77 promoter activity during renal IRI. (A) Induction of GFP transcript level mirrored that of Nur77 in the kidney tissues 24 hours after IRI,Nur77 (also known as TR3 and NGFI-B) is nuclear receptor subfamily 4 group A member 1 (NR4A1) 1, 2, 3, 4.In general, it acts as a transcription factor localized in the nucleus